As already known conception by itself is a genetic juggle and almost 50-60% of abortions in early pregnancy are due to chromosomal abnormalities. So when we manipulate sperms and oocytes outside the human body trying to simulate the natural environment as closely as possible, there is always a similar if not greater risk involved with regard to normalcy of the embryos. This is where the services of PGD come into play. This technique allows a biopsy to be taken from an embryo, preferably in its cleaved state, to ascertain its normal chromosomal status prior to transfer thereby reducing the chances of an abnormal pregnancy. There may be an ethical dilemma as to - should all embryos be biopsied or is there a target population? There are primary indications for PGD which are as listed below:-

• Recurrent miscarriage
• More than two unsuccessful IVF cycles
• Family history of structural chromosomal conditions
• Unexplained Infertility
• Advanced Maternal Age
• Family history of X-linked disease
• Severe Male Factor Infertility
• Single-gene defects

We hope to add this aspect to our existing services in the near future.